Anti-RENT2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-929A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-929A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop... more

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Product information "Anti-RENT2"

Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA. [The UniProt Consortium]

Keywords:	Anti-UPF2, Anti-hUpf2, Anti-KIAA1408, Anti-Nonsense mRNA reducing factor 2, Anti-Up-frameshift suppressor 2 homolog, Anti-Regulator of nonsense transcripts 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-929A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: bovine, dog, horse, rabbit, pig, panda, gorilla, chimpanzee, duckbill platypus, white-tufted-ear marmoset, european domestic ferret, gray short-tailed opossum, small-eared galago, little brown bat, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A303-929A-T maps to a region between residue 1 and 50 of human Regulator of Nonsense Transcripts 2 using the numbering given in entry NP_056357.1 (GeneID 26019).
Format:	Antigen Affinity Purified