Anti-RbAp 46/48

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-25311	50 µg		-	-	3 - 15 business days*		706.00€

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RbAp48 (UniProtKB/Swiss Prot entry Q09028) is a component of several complexes which regulate... more

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Product information "Anti-RbAp 46/48"

RbAp48 (UniProtKB/Swiss Prot entry Q09028) is a component of several complexes which regulate chromatin metabolism. These include (1) the chromatin assembly factor 1 (CAF 1) complex, which is required for chromatin assembly following DNA replication and DNA repair, (2) the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, (3) the nucleosome remodelling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, (4) the PRC2/EED EZH2 complex, which promotes repression of homeotic genes during development, and (5) the NURF (nucleosome remodeling factor) complex. Therefore it may target chromatin assembly factors as well as chromatin remodeling factors and histone deacetylases to their histone substrates in a nucleosomal DNA dependent manner.

Keywords:	RBBP7/4, RBBP-7/4, RBAP46/48, NURF 55,
Supplier:	BPS Bioscience
Supplier-Nr:	25311

Properties

Application:	WB
Antibody Type:	Monoclonal
Conjugate:	No
Species reactivity:	human
Immunogen:	full length human RbAp48 protein (Retinoblastoma binding protein p48) fused to GST. The antibody recognizes both RbAp48 and RbAp46.
Format:	Affinity Purified