Anti-PTBP1 / PTB

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41584.100	100 µl		-	-	6 - 14 business days*		624.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing... more

Close menu

Product information "Anti-PTBP1 / PTB"

Protein function: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806). [The UniProt Consortium]

Keywords:	Anti-PTB, Anti-PTBP1, Anti-hnRNP I, Anti-57 kDa RNA-binding protein PPTB-1, Anti-Polypyrimidine tract-binding protein 1, Anti-Heterogeneous nuclear ribonucleoprotein I
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41584

Properties

Application:	ICC, IF, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide within aa. 1-100 of Human PTBP1 / PTB (NP_114368.1)
Format:	Affinity Purified