Anti-PTBP1 / PTB, N-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG63356.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing... more

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Product information "Anti-PTBP1 / PTB, N-terminal"

Protein function: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. [The UniProt Consortium]

Keywords:	Anti-PTB, Anti-PTBP1, Anti-hnRNP I, Anti-57 kDa RNA-binding protein PPTB-1, Anti-Polypyrimidine tract-binding protein 1, Anti-Heterogeneous nuclear ribonucleoprotein I
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG63356

Properties

Application:	ELISA, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, canine, swine, bovine)
Immunogen:	DGIVPDIAVGTKR-C
Format:	Ammonium Sulfate Precipitated