Anti-PINK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64304.50	50 µg		-	-	6 - 14 business days*		536.00€
ARG64304.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Protects against mitochondrial dysfunction during cellular stress by... more

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Product information "Anti-PINK1"

Protein function: Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291). [The UniProt Consortium]

Keywords:	Anti-BRPK, Anti-PINK1, Anti-PTEN-induced putative kinase protein 1, Anti-Serine/threonine-protein kinase PINK1, mitochondrial
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64304

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	rat (Expected: human, mouse)
Immunogen:	C-QGKAHLESRSYQEAQ
Format:	Ammonium Sulfate Precipitated