Anti-PI3KC3, CT (E834) (Phosphatidylinositol 3-kinase catalytic subunit type 3, PtdIns-3-kinase type

Anti-PI3KC3, CT (E834) (Phosphatidylinositol 3-kinase catalytic subunit type 3, PtdIns-3-kinase type
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039984.200 200 µl - -

1 - 19 business days

557.00€
 
PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme... more
Product information "Anti-PI3KC3, CT (E834) (Phosphatidylinositol 3-kinase catalytic subunit type 3, PtdIns-3-kinase type"
PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway. Applications: Suitable for use in Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Immunohistochemistry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-VPS34, Anti-PIK3C3, Anti-hVps34, Anti-PI3K type 3, EC=2.7.1.137, Anti-PI3-kinase type 3, Anti-PtdIns-3-kinase type 3, Anti-Phosphoinositide-3-kinase class 3, Anti-Phosphatidylinositol 3-kinase p100 subunit
Supplier: United States Biological
Supplier-Nr: 039984

Properties

Application: ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PI3KC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 827~856 amino acids from the C-term region of human PI3KC3.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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