Anti-PI3KC3 (S676) (Phosphatidylinositol 3-kinase catalytic subunit type 3, PtdIns-3-kinase type 3,

Anti-PI3KC3 (S676) (Phosphatidylinositol 3-kinase catalytic subunit type 3, PtdIns-3-kinase type 3,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039981-APC.200 200 µl - -

3 - 19 business days*

993.00€
 
PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme... more
Product information "Anti-PI3KC3 (S676) (Phosphatidylinositol 3-kinase catalytic subunit type 3, PtdIns-3-kinase type 3,"
PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway. Applications: Suitable for use in Immunohistochemistry, FLISA, Recommended Dilution: FLISA: 1:1,000, Immunohistochemistry: 1:10-50, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-VPS34, Anti-PIK3C3, Anti-hVps34, Anti-PI3K type 3, EC=2.7.1.137, Anti-PI3-kinase type 3, Anti-PtdIns-3-kinase type 3, Anti-Phosphoinositide-3-kinase class 3, Anti-Phosphatidylinositol 3-kinase p100 subunit
Supplier: United States Biological
Supplier-Nr: 039981-APC

Properties

Application: FLISA, IHC
Antibody Type: Polyclonal
Conjugate: APC
Host: Rabbit
Species reactivity: human
Immunogen: PI3KC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661~691 amino acids surrounding S676 of human PI3KC3.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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