Anti-phospho-NMDA NR2B Subunit (Ser1166)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-X17	100 µl		-	-	6 - 10 business days*		684.00€

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Anti-Phospho-Ser1166 NMDA Receptor NR2B Subunit Antibody was prepared from rabbit serum by... more

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Product information "Anti-phospho-NMDA NR2B Subunit (Ser1166)"

Anti-Phospho-Ser1166 NMDA Receptor NR2B Subunit Antibody was prepared from rabbit serum by affinity purification via sequential chromatography on phospho and dephosphopeptide affinity columns. Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]

Keywords:	Anti-phospho-NR2B, Anti-phospho-Grin2b, Anti-phospho-GluN2B, Anti-phospho-NMDAR2B, Anti-phospho-Glutamate receptor ionotropic, Anti-phospho-NMDA 2B, Anti-phospho-N-methyl D-aspartate receptor subtype 2B, Anti-phospho-Glutamate [NMDA] receptor subunit epsi
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-X17

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	rat, dog, human, mouse, Xenopus
Immunogen:	Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1166 of rat NMDA Receptor NR2B Subunit conjugated to KLH.
Format:	Purified