101 products were found matching "K05210"!

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BZAD-01
BZAD-01

Item number: Cay38788-1

BZAD-01 is an antagonist of NR2B subunit-containing NMDA receptors (Ki = 72 nM). It is selective for NR2B subunit-containing NMDA receptors over those containing NR2A subunits in a calcium mobilization assay (IC50s = 47 and >10,000 nM, respectively). Oral administration of BZAD-01 reduces hyperalgesia induced by...
Keywords: 4-(trifluoromethoxy)-N-[[2-(trifluoromethyl)phenyl]methyl]-benzenecarboximidamide
Application: NR2B subunit-containing NMDA receptor antagonist
CAS 305339-41-7
MW: 362.3 D
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Mouse GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2B) ELISA Kit
Mouse GRIN2B (Glutamate Receptor, Ionotropic,...

Item number: ELK-ELK8400.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GRIN2B. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GRIN2B....
Keywords: NR2B, Grin2b, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, N-methyl D-aspartate receptor subtype 2B, Glutamate...
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
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Human GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2B) ELISA Kit
Human GRIN2B (Glutamate Receptor, Ionotropic,...

Item number: ELK-ELK4421.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GRIN2B. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GRIN2B....
Keywords: NR3, hNR3, NR2B, GRIN2B, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, N-methyl-D-aspartate receptor subunit 3,...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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D-AP5
D-AP5

Item number: Cay14539-50

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...
Keywords: D-2-Amino-5-Phosphonovaleric Acid, D-APV, 5-phosphono-D-norvaline
Application: NMDA receptor antagonist
CAS 79055-68-8
MW: 197.1 D
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DL-AP5
DL-AP5

Item number: Cay14540-50

DL-AP5 is the racemic version of the selective N-methyl-D-aspartate (NMDA) receptor antagonist, D-AP5 (Cay-14539). Whereas D-AP5 is the active (-)-stereoisomer that competitively inhibits the glutamate binding site of NMDA receptors (Kd = 1.4 µM), the (+)-isomer (L-AP5) demonstrates considerably less potent NMDA...
Keywords: 2-APV, DL-2-Amino-5-Phosphonovaleric acid, 5-phosphono-norvaline
Application: NMDA receptor antagonist
CAS 76326-31-3
MW: 197.1 D
From 64.00€ *
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NMDA
NMDA

Item number: Cay14581-100

NMDA is a synthetic amino acid derivative that acts as a specific agonist at the NMDA receptor, mimicking the excitatory action of the endogenous ligand glutamate. Signaling through the NMDA receptor influences both neuronal plasticity and neurotoxicity. Repetitive activation of NMDA synapses leads to long-term...
Keywords: N-Methyl-D-Aspartic Acid, N-methyl-D-aspartic acid
Application: NMDA receptor agonist
CAS 6384-92-5
MW: 147.1 D
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Anti-phospho-NMDA NR2B Subunit (Tyr1336)
Anti-phospho-NMDA NR2B Subunit (Tyr1336)

Item number: 612-401-C88

Anti-NMDA NR2B Subunit pY1336 antibody is directed against NMDA 2B receptor protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-NMDA NR2B Subunit pY1336 antibody is specific for the phophorylated protein. Immunolabeling of the NMDAR NR2B subunit band is...
Keywords: Anti-phospho-NR2B, Anti-phospho-GluN2B, Anti-phospho-Grin2b, Anti-phospho-NMDAR2B, Anti-phospho-Glutamate receptor...
Application: IHC, WB
Host: Rabbit
Species reactivity: rat
684.00€ *
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Anti-phospho-NMDA R2B (Thr1252)
Anti-phospho-NMDA R2B (Thr1252)

Item number: 612-401-D92

Anti-NMDA R2B pT1252 antibody is directed against NMDA R2B protein. NMDA R2B pT1252 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody is specific for the phophorylated NMDA R2B protein. Immunolabeling of the NMDA NR2B subunit band is blocked by the phosphopeptide...
Keywords: Anti-phospho-NR2B, Anti-phospho-GluN2B, Anti-phospho-Grin2b, Anti-phospho-NMDAR2B, Anti-phospho-Glutamate receptor...
Application: IHC, WB
Host: Rabbit
Species reactivity: rat
684.00€ *
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Gentiopicroside
Gentiopicroside

Item number: LKT-G1855.25

Gentiopicroside is one of the secoiridoid compound isolated from Gentiana lutea. It inhibits morphine dependence through downregulation of GluN2B-containing NMDA receptors in the NAc.
Keywords: 4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b?]dipyran-3-yl]-1,3-benzenediol,...
Application: GRIN2B NMDAR downregulation
CAS 20831-76-9
MW: 356,32 D
From 175.00€ *
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Memantine (hydrochloride)
Memantine (hydrochloride)

Item number: Cay14184-25

Memantine is an NMDA receptor antagonist that blocks NMDA-induced currents in rat retinal ganglion cells by 90% when used at a concentration of 12 µM. It reverses inhibition of dephosphorylation of the synthetic tau phosphopeptide p17 (tau194-207) induced by the endogenous inhibitor of protein phosphatase 2A (PP2A)...
Keywords: Akatinol, Axura, Ebix, Namenda, NSC 102290, SUN Y7017, 3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride
Application: NMDA open-channel blocker
CAS 41100-52-1
MW: 215.8 D
From 35.00€ *
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Eliprodil
Eliprodil

Item number: Cay18398-5

N-Methyl-D-aspartate (NMDA) receptors are calcium permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. Eliprodil is a non-competitive NMDA receptor antagonist that inhibits neuronal calcium channel currents. It is selective for NR2B...
Keywords: SL 820715, alpha-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol
Application: Selective NMDA glutamate receptor NR2B antagonist
CAS 119431-25-3
MW: 347.9 D
From 82.00€ *
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Amantadine (hydrochloride)
Amantadine (hydrochloride)

Item number: Cay21364-25

Amantadine is an NMDA receptor antagonist with IC50 values of 0.93, 0.82, and 0.47 µM at -70 mV for NR1-1a/NR2A, NR1-1a/NR2B, and NR1-1a/NR2D subunit-containing recombinant receptors, respectively, expressed in HEK293 cells. It blocks the influenza A M2 proton channel (IC50 = 16 µM for the recombinant channel...
Keywords: Adamantylamine, Aminoadamantane, NSC 83653, tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride
Application: NMDA receptor antagonist, antiviral, M2 protein inhibitor
CAS 665-66-7
MW: 187.7 D
From 43.00€ *
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