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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
612-401-D92 | 100 µl | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-NMDA R2B pT1252 antibody is directed against NMDA R2B protein. NMDA R2B pT1252 antibody was... more
Product information "Anti-phospho-NMDA R2B (Thr1252)"
Anti-NMDA R2B pT1252 antibody is directed against NMDA R2B protein. NMDA R2B pT1252 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody is specific for the phophorylated NMDA R2B protein. Immunolabeling of the NMDA NR2B subunit band is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide. Immunolabeling is also blocked by ?-phosphatase treatment. The antibody may also show some slight reactivity with Tyr1246 of NR2A. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, chicken, human, mouse, non-human primate and zebra fish. Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2 influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]
Keywords: | Anti-phospho-NR2B, Anti-phospho-GluN2B, Anti-phospho-Grin2b, Anti-phospho-NMDAR2B, Anti-phospho-Glutamate receptor ionotropic, NMDA 2B, Anti-phospho-N-methyl D-aspartate receptor subtype 2B, Anti-phospho-Glutamate [NMDA] receptor subunit epsilon-2 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 612-401-D92 |
Properties
Application: | IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | rat |
Immunogen: | synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1252. |
Format: | Purified |
Database Information
KEGG ID : | K05210 | Matching products |
UniProt ID : | Q00960 | Matching products |
Gene ID | GeneID 24410 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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