Products from ORF Genetics
ORF Genetics is an innovative Icelandic biotechnology company founded in 2001 that uses plants to produce high-quality recombinant proteins in a sustainable, scalable way. At the heart of ORF Genetics’ work is its proprietary Orfeus™ molecular farming platform, which harnesses bioengineered barley grains as mini-factories to express human and animal growth factors and cytokines. This plant-based production system yields highly pure, animal origin-free, and endotoxin-free proteins for use in stem cell research, regenerative medicine and organoid culture. The ISOkine® product line is designed to meet the highest standards for life science research, offering consistent quality, excellent batch-to-batch reproducibility and suitability for advanced life-science applications.
More information at: www.orfgenetics.com
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TNF-alpha, rHuman, Animal Free, High Purity/Bioactive
Item number: ORF-IK2600-10ug
Description TNF-alpha (Tumor necrosis factor, alpha), a member of the TNF ligand superfamily, is among others, secreted by macrophages, activated monocytes, neutrophils, T-cells, B-cells and natural killer cells stimulated by bacterial lipopolysaccharides. TNF-alpha shows approximately 30% homology with TNF-beta....
| Keywords: | TNF, TNF-alpha, Cachectin, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2 |
| Application: | Cell culture, Bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 196 kD |
67.00€
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From 46.90€
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LIF, rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK0700-5x10ug
Leukemia inhibitory factor (LIF) is a pleiotropic lymphoid factor belonging to the interleukin-6 family of cytokines. It was initially described as a factor inhibiting the proliferation of myeloid leukemia cells and inducing their differentiation into macrophages. Other activities of LIF include inhibition of...
| Keywords: | LIF, Leukemia inhibitory factor, Melanoma-derived LPL inhibitor, Differentiation-stimulating factor |
| Application: | Cell culture, bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 218 kD |
100.00€
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From 70.00€
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EGF, rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK0100-1000ug
Epidermal Growth Factor (EGF) is a potent growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation. It stimulates the proliferation of various epidermal and epithelial cells. EGF has been shown to inhibit gastric secretion, promote colony formation of epidermal...
| Keywords: | EGF, Pro-epidermal growth factor |
| Application: | Cell culture, bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 7 kD |
33.00€
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From 23.10€
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FGFb / FGF2 rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK0200-1000ug
FGF-basic (bFGF or FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members are heparin-binding multifunctional proteins and are involved in a variety of biological processes including angiogenesis, wound healing, and embryonic development. FGF-basic is known to play a key role during...
| Keywords: | FGF2, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2 |
| Application: | Cell culture, bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 178 kD |
80.00€
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From 56.00€
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IGF1 LR3 (IGF-1) rHuman Animal Free High Purity/Bioactivity
Item number: ORF-IK0300-1000ug
The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the...
| Keywords: | IGF1, Somatomedin-C, Mechano growth factor, Insulin-like growth factor I, Insulin-like growth factor 1 |
| Application: | Cell culture, Bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 91 kD |
33.00€
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From 23.10€
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IL-6 rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK0400-1000ug
Interleukin 6, IL-6, is a multifunctional cytokine with an essential role in host defense by regulating immune and inflammatory responses. It is expressed by various cell types, including T cells, B cells, monocytes/macrophages, fibroblasts, and possibly tumor cells. IL-6 has diverse biological functions,...
| Keywords: | IL6, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor, B-cell stimulatory factor 2 |
| Application: | Cell culture, bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
100.00€
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From 70.00€
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VEGF 165, rHuman, Animal Free,High Purity/Bioactivit
Item number: ORF-IK0500-1000ug
VEGF (Vascular endothelial growth factor) is the only growth factor that stimulates vascular permeability. It promotes endothelial proliferation and survival, angiogenesis, vasculognesis and inhibits apoptosis. VEGF mitogenic activity is specific for endothelial cell and that makes it distinct among other growth...
| Keywords: | VEGFA, Vascular permeability factor, Vascular endothelial growth factor A, long form |
| Application: | Cell culture, Bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 213 kD |
166.00€
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From 116.20€
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KGF / FGF 7, rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK0600-1000ug
Keratinocyte Growth Factor (KGF, FGF 7, HBGF 7) is a member of the FGF family of 23 related mitogenic proteins. These proteins play a central role during embryonic development and postnatal growth and tissue repair, by promoting cellular proliferation and differentiation. KGF specifically stimulates epithelial cells...
| Keywords: | FGF7, Fibroblast growth factor 7, Keratinocyte growth factor, Heparin-binding growth factor 7 |
| Application: | Cell culture, bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 212 kD |
166.00€
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From 116.20€
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LIF mouse, Animal Free, High Purity/Bioactivity,...
Item number: ORF-IK0701-1000ug
LIF (leukemia inhibitory factor, myeloid leukemia inhibitory factor) a pleiotropic lymphoid factor was initially described as a factor that inhibits the proliferation of myeloid leukemia cells and induces their differentiation into macrophages. Other activities of LIF include inhibition of adipogenesis, cholinergic...
| Keywords: | Lif, Leukemia inhibitory factor, Differentiation-stimulating factor |
| Application: | Cell culture, Bioassay |
| Expressed in: | Barley grain |
| Origin: | mouse |
| MW: | 212 kD |
133.00€
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From 93.10€
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GDNF, rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK0900-1000ug
Glial cell line derived neurotrophic factor (GDNF) is a protein promoting the survival of various neuronal subpopulations at different stages of development. These include dopaminergic neurons in midbrain, GDNF stimulates their survival, differentiation, and high-affinity dopamine uptake. The use of GDNF in the...
| Keywords: | GDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor |
| Application: | Cell culture, bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 172 kD |
166.00€
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From 116.20€
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PDGF bb, rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK1000-1000ug
Platelet-Derived Growth Factor-BB (PDGF-BB) is a disulfide-linked homodimer of two B-chains (109 aa each). It is stored in platelet alpha-granules and is released following activation of platelets. PDGF-BB has potent mitogenic effects on various cell types such as cells of connective tissue, bone and cartilage, and...
| Keywords: | PDGFB, PDGF-2, Proto-oncogene c-Sis, Platelet-derived growth factor B chain, Platelet-derived growth factor subunit B,... |
| Application: | Cell culture, Bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
133.00€
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From 93.10€
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Flt3-ligand, rHuman, Animal Free, High Purity/Bioactivity
Item number: ORF-IK1700-1000ug
Flt3-ligand (FMS related tyrosine kinase 3 ligand, flk-2 ligand) is involved in proliferation and differentiation of early hematopoietic cells. Flt3-ligand synergizes with other CSF's and interleukins to induce proliferation of early hematopoietic cells but does not stimulate growth or differentiation alone....
| Keywords: | FLT3LG, SL cytokine, Fms-related tyrosine kinase 3 ligand |
| Application: | Cell culture, Bioassay |
| Expressed in: | Barley grain |
| Origin: | human |
| MW: | 199 kD |
166.00€
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From 116.20€
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