Anti-PDE8A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA007722.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA007722.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many... more

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Product information "Anti-PDE8A"

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1 'Ser-259' inhibitory- phosphorylation and stimulates RAF1-dependent EGF-activated ERK- signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 79% and to rat: 80%

Keywords:	Anti-PDE8A, Anti-High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA007722

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TTMGYQSGEL IGKELGEVPI NEKKADLLDT INSCIRIGKE WQGIYYAKKK NGDNIQQNVK IIPVIGQGGK IRHYVSIIRV CNGNNKAEKI SECVQSDTHT DNQTGKHKDR RKGSLDVKAV ASRATEVSSQ RRHSS (ATA-APrEST77924)