20 products were found matching "O60658"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PDE8A antibody detects Phosphodiesterase 8A, an enzyme that specifically hydrolyzes cyclic adenosine monophosphate (cAMP) to AMP, thereby regulating intracellular signaling pathways mediated by this second messenger. PDE8A belongs to the type...

Active human PDE8A1 (GenBank Accession No. NM_002605), full length with N-terminal GST tag, MW= 119 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. [The UniProt Consortium]

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. [The UniProt Consortium]

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE8 is involved in many biological processes, including T-cell activation, testosterone production, adrenocortical hyperplasia, and thyroid function. The PDE8A Assay Kit is designed for identification of PDE8A...

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1...

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1...

Custom conjugation services for this antibody as available (eg. labeling of Anti-Purified Mouse Anti-human PDE8A *EM-52, monoclonal* with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750,...

Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1...

PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Applications:...

Full length recombinant corresponding to human PDE8A1 with an N-terminal GST tag, expressed in a Baculovirus infected Sf9 cell expression system. Genebank: NM_002605. Specific Activity: As reported, Unit Definition: 1 unit is the amount of PDE8A1 that will convert 1 pmole 3', 5'-cAMP to 5'-AMP per minute at 37°C....