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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG42604.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins... more
Product information "Anti-PARP2"
Protein function: Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:28190768, PubMed:25043379). Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D- ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of glutamate and aspartate residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units (PubMed:25043379). ADP-ribosylation follows DNA damage and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Also mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (PubMed:28190768). In addition to proteins, also able to ADP-ribosylate DNA: preferentially acts on 5'- terminal phosphates at DNA strand breaks termini in nicked duplex (PubMed:27471034). [The UniProt Consortium]
| Keywords: | Anti-ARTD2, Anti-PARP2, Anti-ADPRT2, Anti-PARP-2, Anti-hPARP-2, Anti-ADPRT-2, Anti-pADPRT-2, Anti-Poly[ADP-ribose] synthase 2, Anti-Poly [ADP-ribose] polymerase 2, Anti-NAD(+) ADP-ribosyltransferase 2, Anti-DNA ADP-ribosyltransferase PARP2 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG42604 |
Properties
| Application: | FC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Synthetic peptide derived from Human PARP2 |
| MW: | 66 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K10798 | Matching products |
| UniProt ID : | Q9UGN5 | Matching products |
| Gene ID | GeneID 10038 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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