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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PACSIN1 (Protein Kinase C And Casein Kinase Substrate In Neurons 1) is a Protein Coding gene.... more
Product information "Anti-PACSIN1"
PACSIN1 (Protein Kinase C And Casein Kinase Substrate In Neurons 1) is a Protein Coding gene. Diseases associated with PACSIN1 include Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Vesicle-mediated transport and Clathrin-mediated endocytosis. Gene Ontology (GO) annotations related to this gene include phospholipid binding and cytoskeletal protein binding. An important paralog of this gene is PACSIN2. Protein function: Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT, this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis, this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission. Binds to membranes via its F-BAR domain and mediates membrane tubulation. [The UniProt Consortium]
Keywords: | Anti-PACSIN1, Anti-KIAA1379, Anti-Syndapin-1, Anti-Protein kinase C and casein kinase substrate in neurons protein 1, PACSIN1 Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-66596 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant fusion protein of human PACSIN1 (NP_065855.1). |
Database Information
KEGG ID : | K20123 | Matching products |
UniProt ID : | Q9BY11 | Matching products |
Gene ID | GeneID 29993 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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