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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| A300-579A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
| A300-579A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a... more
Product information "Anti-NF2"
Protein function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. [The UniProt Consortium]
| Keywords: | Anti-NF2, Anti-SCH, Anti-Merlin, Anti-Schwannomin, Anti-Schwannomerlin, Anti-Neurofibromin-2, Anti-Moesin-ezrin-radixin-like protein |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | A300-579A |
Properties
| Application: | WB, IP |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human (Expected: rat) |
| Immunogen: | synthetic peptide. The epitope recognized by A300-579A-T maps to a region between residue 550 and the C-terminus (residue 590) of human Neurofibromin 2 in entry NP_057502.2 (GeneID 4771). This epitope is common to NF2 isoforms 2, 5 (NP_861966.1), 6 (NP_861967.1) and 7 (NP_861968.1). |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K16684 | Matching products |
| UniProt ID : | P35240 | Matching products |
| Gene ID | GeneID 4771 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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