Anti-MMP14 / MT1-MMP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57721.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Endopeptidase that degrades various components of the extracellular matrix such... more

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Product information "Anti-MMP14 / MT1-MMP"

Protein function: Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140). [The UniProt Consortium]

Keywords:	Anti-MMP14, Anti-MMP-14, Anti-MT1MMP, Anti-MTMMP1, Anti-MMP-X1, Anti-MT1-MMP, Anti-MT-MMP 1, EC=3.4.24.80, Anti-Matrix metalloproteinase-14, Anti-Membrane-type matrix metalloproteinase 1, Anti-Membrane-type-1 matrix metalloproteinase
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57721

Properties

Application:	FC, ICC, IF, IHC (paraffin), IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide from Human MMP14 / MT1-MMP
Format:	Affinity Purified