Anti-Menin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-106A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-106A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a... more

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Product information "Anti-Menin"

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair. [The UniProt Consortium]

Keywords:	Anti-SCG2, Anti-MEN1, Anti-Menin
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-106A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, bovine, dog)
Immunogen:	synthetic peptide. The epitope recognized by A300-106A-T maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Format:	Antigen Affinity Purified