Anti-Menin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG10827.50	50 µg		-	-	6 - 14 business days*		528.00€

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Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a... more

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Product information "Anti-Menin"

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair. [The UniProt Consortium]

Keywords:	Anti-SCG2, Anti-MEN1, Anti-Menin
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG10827

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Recombinant protein around aa. 301-615 of Human Menin
MW:	68 kD
Format:	Antigen Affinity Purified