29 products were found matching "K14970"!
No results were found for the filter!
Anti-Menin
Item number: A300-105A
Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
| Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 164.00€
*
MI-2 (hydrochloride)
Item number: Cay11620-1
Menin, a product of the multiple endocrine neoplasia gene, is an essential component of histone methyltransferase complexes involving the mixed lineage leukemia (MLL) gene product. Also, the leukemogenic activity of MLL fusion proteins depends on their direct interaction with menin. MI-2 potently binds menin, blocks...
| Keywords: | 4-(4-(5,5-dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-propylthieno[2,3-d]pyrimidine, dihydrochloride |
| Application: | Menin binding |
| MW: | 448.5 D |
From 50.00€
*
MI-nc (hydrochloride)
Item number: Cay11621-1
Menin, a product of the multiple endocrine neoplasia gene, is an essential component of histone methyltransferase complexes involving the mixed lineage leukemia (MLL) gene product. Also, the leukemogenic activity of MLL fusion proteins depends on their direct interaction with menin. MI-nc is a weak inhibitor of the...
| Keywords: | 6-ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]-thieno[2,3-d]pyrimidine, dihydrochloride |
| Application: | Menin-MLL inhibitor, Negative control |
| CAS | 1934302-23-4 |
| MW: | 405.4 D |
From 84.00€
*
Anti-Menin
Item number: A300-115A
Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
| Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human |
From 164.00€
*
Anti-Menin (IHC)
Item number: IHC-00572
Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
| Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 164.00€
*
MI-2
Item number: Cay29218-5
MI-2 is an inhibitor of the protein-protein interaction between menin and mixed lineage leukemia (MLL) fusion proteins (IC50 = 446 nM). It binds to menin (Kd = 158 nM) and inhibits the menin interaction with the MLL fusion protein MLL-AF9 in HEK293 cells without affecting protein levels of menin or MLL-AF9. MI-2...
| Keywords: | 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propyl-thieno[2,3-d]pyrimidine |
| Application: | Menin-MLL fusion protein interaction inhibitor |
| CAS | 1271738-62-5 |
| MW: | 375.6 D |
From 130.00€
*
Anti-Menin
Item number: ARG10827.50
Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
| Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
528.00€
*
Anti-Menin
Item number: A300-106A
Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
| Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin |
| Application: | WB, IP |
| Host: | Goat |
| Species reactivity: | human |
From 164.00€
*
Human Secretogranin 2 / Chromogranin C ELISA Kit
Item number: G-HUFI02838.96
| Application: | ELISA |
| Species reactivity: | human |
641.00€
*
Anti-Menin
Item number: NSJ-R31676
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The MEN1 gene encodes Menin, a nuclear scaffold protein that regulates gene transcription by coordinating chromatin remodeling. It is mapped to 11q13.1. MEN1 is considered to act as a tumor suppressor gene. It has been found that that MEN1 inactivation by...
| Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin, Menin Antibody |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
755.00€
*
Anti-Menin / MEN1, clone ACBA-13
Item number: NSJ-RQ4687
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation....
| Keywords: | Anti-SCG2, Anti-MEN1, Anti-Menin, Menin Antibody / MEN1 |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
755.00€
*
MI-3
Item number: Cay27214-1
MI-3 is an inhibitor of the interaction between menin and mixed lineage leukemia (MLL) fusion proteins (IC50 = 648 nM). MI-3 binds to menin (Kd = 201 nM) and inhibits the menin interaction with the MLL fusion protein MLL-AF9 in HEK293 cells without affecting protein levels of menin or MLL-AF9. It inhibits growth of...
| Keywords: | 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(1-methylethyl)-thieno[2,3-d]pyrimidine |
| Application: | MLL / menin interaction inhibitor |
| CAS | 1271738-59-0 |
| MW: | 375.6 D |
From 50.00€
*