Anti-MDR1 / P Glycoprotein 1 (PE), clone UIC2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG42284.50	50 tests		-	-	6 - 14 business days*		520.00€

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Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203,... more

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Product information "Anti-MDR1 / P Glycoprotein 1 (PE), clone UIC2"

Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218). [The UniProt Consortium]

Keywords:	Anti-MDR1, Anti-CD243, EC=7.6.2.2, Anti-P-glycoprotein 1, Anti-Phospholipid transporter ABCB1, Anti-Multidrug resistance protein 1, Anti-ATP-dependent translocase ABCB1, Anti-ATP-binding cassette sub-family B member 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG42284

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	UIC2
Conjugate:	Phycoerythrin
Host:	Mouse
Species reactivity:	human
Immunogen:	NIH/3T3 cells transfected with Human MDR1 cDNA
MW:	141 kD
Format:	Purified