202 products were found matching "K05658"!

0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. CD243 antibody, also known as Multidrug Resistance 1 antibody, recognizes a plasma membrane-associated ATP-dependent efflux transporter encoded by the ABCB1 gene. CD243 is the cluster of differentiation designation for the protein commonly referred to as...

0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. MDR1 antibody, also known as Multidrug resistance protein 1 antibody, recognizes a transmembrane ATP-dependent drug efflux transporter encoded by the ABCB1 gene. Multidrug resistance protein 1, commonly referred to as P-glycoprotein and CD243, is a member of...

1 mg/ml in 1X PBS, BSA free, sodium azide free. MDR1 antibody, also known as Multidrug resistance protein 1 antibody, recognizes a transmembrane ATP-dependent drug efflux transporter encoded by the ABCB1 gene. Multidrug resistance protein 1, commonly referred to as P-glycoprotein and CD243, is a member of the...

1 mg/ml in 1X PBS, BSA free, sodium azide free. CD243 antibody, also known as Multidrug Resistance 1 antibody, recognizes a plasma membrane-associated ATP-dependent efflux transporter encoded by the ABCB1 gene. CD243 is the cluster of differentiation designation for the protein commonly referred to as P-glycoprotein...

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)....

Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp, also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem...

Tariquidar is an anthranilic acid derivative that binds to P-glycoprotein (Kd = 5.1 nM) and inhibits transport activity. It inhibits transport of vinblastine (Cay-11762) and paclitaxel (Cay-10461) in multidrug resistant CHrB30 cells, increasing the steady state accumulation to non-P-glycoprotein-expressing multidrug...

Protein function: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. [The UniProt Consortium]

Nobiletin is a polymethoxylated flavonoid that has been found in C. unshiu and has diverse biological activities. It reduces LPS- and IFN-gamma-induced increases in inducible nitric oxide synthase (iNOS) protein levels and NO production in RAW 264.7 cells when used at concentrations of 25, 50, and 100 µM. Nobiletin...

Zosuquidar is a modulator of P-glycoprotein (P-gp, Ki = 59 nM). It restores the sensitivity of P-gp-expressing cancer cells to vinblastine (Cay-11762), doxorubicin (Cay-15007), etoposide (Cay-12092), and paclitaxel (Cay-10461) when used at 0.1 µM. It less potently inhibits cytochrome P450 (CYP) isoforms CYP3A,...

Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. P Glycoprotein, also called MDR1, P-GP, and PGY1, is a protein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. It is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular...