Anti-LRRC8E

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA020466.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA020466.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named... more

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Product information "Anti-LRRC8E"

Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24790029, PubMed:26824658, PubMed:28193731). The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine (PubMed:24790029, PubMed:26824658). Mediates efflux of amino acids, such as aspartate, in response to osmotic stress (PubMed:28193731). Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658, PubMed:28193731). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 88% and to rat: 89%

Keywords:	Anti-LRRC8E, Anti-Leucine-rich repeat-containing protein 8E, Anti-Volume-regulated anion channel subunit LRRC8E
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA020466

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KLRQKLQRNA AGRLELALCM LPGLPDTVFE LSEVESLRLE AICDITFPPG LSQLVHLQEL SLLHSPARLP FSLQVFLRDH LKVMRVKCEE LREVPLWVFG LRGLEELHLE GLFPQELARA ATL (ATA-APrEST73065)