24 products were found matching "K22038"!
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Endovion
Item number: TGM-T15233-100mg
Description: Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker. Target: Chloride channel. Smiles: FC(F)(F)c1cc(NC(=O)Nc2ccc(Br)cc2-c2nn[nH]n2)cc(c1)C(F)(F)F. References: Sørensen BH, et al. Downregulation of LRRC8A...
| Keywords: | NS3728 |
| Application: | Chloride channel inhibitor |
| CAS | 265646-85-3 |
| MW: | 495.18 D |
From 31.00€
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DCPIB
Item number: Cay34064-5
DCPIB is an inhibitor of volume-regulated anion channels (VRAC). It inhibits the swelling-induced chloride current (ICl,swell) in bovine pulmonary artery endothelial cells (IC50 = 4.1 µM). DCPIB inhibits the VRAC subunit leucine-rich containing 8A (LRRC8A, IC50 = 20.9 µM) and inhibits sphingosine-1-phosphate-induced...
| Keywords: | 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-butanoic acid |
| Application: | VRAC inhibitor |
| CAS | 82749-70-0 |
| MW: | 427.4 D |
From 100.00€
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Anti-LRRC8A
Item number: A304-175A
Protein function: Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic...
| Keywords: | Anti-LRRC8A, Anti-KIAA1437, Anti-Swelling protein 1, Anti-Leucine-rich repeat-containing protein 8A, Anti-Volume-regulated... |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 178.00€
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Anti-LRRC8E
Item number: G-PACO36750.50
LRRC8E Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC, IF applications. LRRC8E Antibody is a high quality polyclonal antibody for research use only.. Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC...
| Keywords: | Anti-LRRC8E, Anti-Leucine-rich repeat-containing protein 8E, Anti-Volume-regulated anion channel subunit LRRC8E |
| Application: | ELISA, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
384.00€
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Anti-LRRC8E
Item number: ATA-HPA020466.100
Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24790029, PubMed:26824658, PubMed:28193731). The VRAC channel conducts...
| Keywords: | Anti-LRRC8E, Anti-Leucine-rich repeat-containing protein 8E, Anti-Volume-regulated anion channel subunit LRRC8E |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 358.00€
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Anti-LRRC8B
Item number: ATA-HPA017950.100
Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24790029, PubMed:26824658, PubMed:28193731). The VRAC channel conducts...
| Keywords: | Anti-LRRC8B, Anti-TA-LRRP, Anti-KIAA0231, Anti-Leucine-rich repeat-containing protein 8B, Anti-T-cell activation leucine... |
| Application: | ICC, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 239.00€
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NS 3623
Item number: Cay34992-10
NS 3623 is an ion channel modulator. It inhibits the volume-regulated anion channel (VRAC) in HEK293 cells and chloride conductance in isolated human red blood cells (IC50s = 1.8 and 0.21 µM, respectively). NS 3623 also activates human-ether-a-go-go (hERG), also known as Kv11.1 (EC50 = 79.4 µM) but does not activate...
| Keywords: | N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea |
| Application: | Ion channel modulator, VRAC inhibitor |
| CAS | 343630-41-1 |
| MW: | 427.2 D |
From 130.00€
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NS 3728
Item number: Cay39988-10
NS 3728 is a chloride channel inhibitor. It inhibits the volume-regulated anion channel (VRAC) in HEK293 cells and chloride conductance in washed isolated human erythrocytes (IC50s = 0.4 and 0.6 µM, respectively). NS 3728 also inhibits calcium-activated chloride currents in Ehrlich-Lettre ascites carcinoma cells...
| Keywords: | Endovion, SCO 101, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-urea |
| Application: | Chloride channel inhibitor |
| CAS | 265646-85-3 |
| MW: | 495.2 D |
From 136.00€
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LRRC8D (human), recombinant protein
Item number: ABS-PQ-724.20
| Keywords: | Volume-regulated anion channel subunit LRRC8D, Leucine-rich repeat-containing protein 5, Leucine-rich repeat-containing... |
| Expressed in: | human cells |
| Origin: | human |
| MW: | 37.5 kD |
From 270.00€
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Anti-LRRC8C
Item number: CSB-PA013170GA01HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen Affinity Purified. Target Name: LRRC8C. Antigen Species: Human
| Keywords: | Anti-AD158, Anti-LRRC8C, Anti-Factor for adipocyte differentiation 158, Anti-Leucine-rich repeat-containing protein 8C,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
552.00€
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Anti-LRRC8D
Item number: CSB-PA013171GA01HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen Affinity Purified. Target Name: LRRC8D. Antigen Species: Human
| Keywords: | Anti-LRRC5, Anti-LRRC8D, Anti-Leucine-rich repeat-containing protein 5, Anti-Leucine-rich repeat-containing protein 8D,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
552.00€
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Anti-LRRC8E
Item number: CSB-PA743982LA01HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: LRRC8E. Antigen Species: Human
| Keywords: | Anti-LRRC8E, Anti-Leucine-rich repeat-containing protein 8E, Anti-Volume-regulated anion channel subunit LRRC8E, LRRC8E... |
| Application: | ELISA, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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