Anti-LRRC8B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA017950.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA017950.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named... more

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Product information "Anti-LRRC8B"

Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24790029, PubMed:26824658, PubMed:28193731). The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658, PubMed:28193731). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 92%

Keywords:	Anti-LRRC8B, Anti-TA-LRRP, Anti-KIAA0231, Anti-Leucine-rich repeat-containing protein 8B, Anti-T-cell activation leucine repeat-rich protein, Anti-Volume-regulated anion channel subunit LRRC8B
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA017950

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PSTSSRLEHF VAILHKCFDS PWTTRALSET VAEQSVRPLK LSKSKILLSS SGCSADIDSG KQSLPYPQPG LESAGIESPT SSVLDKKEGE QAKAIFEKVK RFRMHVEQKD (ATA-APrEST73184)