Anti-KEAP1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG58946.50 50 µg - -

6 - 14 business days*

520.00€
 
Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed... more
Product information "Anti-KEAP1"
Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. [The UniProt Consortium]
Keywords: Anti-INRF2, Anti-INrf2, Anti-KEAP1, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like ECH-associated protein 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG58946

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: A 19 amino acid synthetic peptide (within the last 50 aa) of Human KEAP1
MW: 69 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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