- Search results for Q14145
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49 products were found matching "Q14145"!
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Item number: ELK-ELK7324.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KEAP1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KEAP1. Next,...
Keywords: | INrf2, Kelch-like protein 19, Cytosolic inhibitor of Nrf2, Kelch-like ECH-associated protein 1 |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: BPS-72020
The Keap1:Nrf2 Inhibitor Screening Assay Kit is designed for identification of inhibitors of Keap1:Nrf2 binding using fluorescence polarization. Using this kit, only one simple step on a microtiter plate is required for Keap1:Nrf2 inhibitor screening reactions. The Keap1 protein and fluorescently labeled Nrf2...
Keywords: | INrf2, Kelch-like protein 19, Cytosolic inhibitor of Nrf2, Kelch-like ECH-associated protein 1, |
Application: | Inhibitor screening, drug discovery, HTS |
Species reactivity: | human |
1,403.00€
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Item number: Cay32035-100
Kelch-like ECH-associated protein 1 (Keap1) is a substrate adapter protein in the Kelch-like (KLHL) family of proteins. It contains an N-terminal region, a BTB/POZ domain that facilitates protein binding and Keap1 dimerization, a central intervening region (IVR), a double glycine repeat (DGR)/Kelch repeat domain, a...
Keywords: | Cytosolic Inhibitor of Nrf2, INRF2, Kelch-Like ECH-Associated Protein 1, KLHL19 |
Expressed in: | Insect cells |
Origin: | human |
MW: | 97.37 kD |
439.00€
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Item number: BPS-70040-1
Human Keap1, also known as Kelch-like ECH-associated protein, INRF2, KIAA0132, and KLHL19, GenBank Accession No. NM_203500, a.a. 321-609 expressed in an E. coli cell expression system. MW = 32.6 kDa
Keywords: | INrf2, Kelch-like protein 19, Cytosolic inhibitor of Nrf2, Kelch-like ECH-associated protein 1, |
Application: | Protein binding studies, small molecule screening |
Expressed in: | E.coli |
Origin: | human |
MW: | 32,6 kD |
From 752.00€
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Item number: NSJ-R32225
0.5mg/ml if reconstituted with 0.2ml sterile DI water. KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 is a protein that in humans is encoded by the KEAP1 gene. Keap1 contains a central BTB/POZ domain and a C-terminal double glycine repeat (DGR), or Kelch, module. Keap1 has been shown to interact with Nrf2, a master regulator...
Keywords: | Anti-INRF2, Anti-INrf2, Anti-KEAP1, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
755.00€
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Item number: NSJ-R34041-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Kelch-like ECH-associated protein 1 Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination...
Keywords: | Anti-INrf2, Anti-INRF2, Anti-KEAP1, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like... |
Application: | WB, IHC, ELISA (peptide) |
Host: | Goat |
Species reactivity: | human, mouse |
755.00€
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Item number: NSJ-F40314-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by...
Keywords: | Anti-INrf2, Anti-INRF2, Anti-KEAP1, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like... |
Application: | WB, ELISA |
Host: | Mouse |
Species reactivity: | human |
From 326.00€
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Item number: NSJ-F40464-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. KEAP1 acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of...
Keywords: | Anti-INrf2, Anti-INRF2, Anti-KEAP1, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like... |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 326.00€
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Item number: G-HUFI03108.96
Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated...
Keywords: | INRF2, KEAP1, INrf2, Kelch-like protein 19, Cytosolic inhibitor of Nrf2, Kelch-like ECH-associated protein 1 |
641.00€
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Item number: E-AB-60460.120
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus....
Keywords: | Anti-KEAP1, Anti-INrf2, Anti-INRF2, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like... |
Application: | WB, IHC, IF |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: ARG58946.50
Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated...
Keywords: | Anti-INRF2, Anti-INrf2, Anti-KEAP1, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
520.00€
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Item number: ARG66711.100
Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination (PubMed:14585973, PubMed:15379550, PubMed:15572695, PubMed:15983046, PubMed:15601839). KEAP1 acts as a key sensor of oxidative...
Keywords: | Anti-INrf2, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like ECH-associated protein 1 |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human |
624.00€
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