Anti-KDM7A

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA012114.25 25 µl -

7 - 10 business days*

335.00€
ATA-HPA012114.100 100 µl -

7 - 10 business days*

446.00€
 
Protein function: Histone demethylase required for brain development. Specifically demethylates... more
Product information "Anti-KDM7A"
Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 92%
Keywords: Anti-KDM7A, Anti-JHDM1D, EC=1.14.11.-, Anti-Lysine-specific demethylase 7, Anti-Lysine-specific demethylase 7A, Anti-JmjC domain-containing histone demethylation protein 1D
Supplier: Atlas Antibodies
Supplier-Nr: HPA012114

Properties

Application: ICC, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LETLKELRED GFQPQTYLVQ GVKALHTALK LWMKKELVSE HAFEIPDNVR PGHLIKELSK VIRAIEEENG KPVKSQGIPI VCPVSRSSNE A (ATA-APrEST71307)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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