22 products were found matching "K11445"!

Human JHDM1D, also known as Lysine-specific demethylase 7A (KDM7A) and KIAA1718, GenBank Accession No. NM_030647 a.a. 2-488 with an N-terminal FLAG-tag, MW=56 kDa, expressed in a baculovirus-infected Sf9 cell expression system.

The JHDM1D Homogeneous Assay Kit is designed to measure activity of JHDM1D for screening and profiling applications. JHDM1D, also known as KDM7A and KIAA1718, is a JumonjiC (JmjC) domain-containing histone lysine demethylase that exhibits demethylation activity toward dimethyl-lysine 9 and dimethyl-lysine 27 on...

TC-E 5002 is an inhibitor of the histone lysine demethylase (KDM) subfamily KDM2/7 (IC50s = 6.8, 0.2, and 1.2 µM for KDM2A, KDM7A, and KDM7B, respectively). It is selective for the KDM2/7 subfamily over KDM4A, KDM4C, KDM5A, and KDM6A/UTX (IC50s = >120, 83, 55, and 100 µM, respectively). It inhibits the growth of...

Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds...

KDM7A (Lysine Demethylase 7A) is a Protein Coding gene. Among its related pathways are Chromatin organization and Oncogenic MAPK signaling. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular...

The JHDM1D Chemiluminescent Assay Kit is designed to measure JHDM1D activity for screening and profiling applications. JHDM1D, also known as KDM7A and KIAA1718, is a JumonjiC (JmjC) domain-containing histone lysine demethylase that exhibits demethylation activity toward dimethyl-lysine 9 and dimethyl-lysine 27 on...

KDM7A (Lysine Demethylase 7A) is a Protein Coding gene. Diseases associated with KDM7A include Syndromic X-Linked Intellectual Disability Siderius Type. Among its related pathways are Chromatin organization and Oncogenic MAPK signaling. Gene Ontology (GO) annotations related to this gene include iron ion binding and...

Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds...

Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds...

Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9', 'Lys-27' and 'Lys-36' (H3K9me2, H3K27me2, H3K36me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code...

The 4x HDM Assay Buffer 3 is optimized for use with the following BPS Bioscience histone demethylase assay kits: * JMJD2C (KDM4C) Homogeneous Assay Kit, BPS-50415 * JMJD2E (KDM4DL) Homogeneous Assay Kit, BPS-50417 * JMJD3 (KDM6B) Homogeneous Assay Kit, BPS-50416 * PHF8 (KDM7B) Homogeneous Assay Kit, BPS-50515