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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES19795.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
| ELK-ES19795.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Histone demethylase required for brain development. Specifically demethylates... more
Product information "Anti-KDM7"
Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9', 'Lys-27' and 'Lys-36' (H3K9me2, H3K27me2, H3K36me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code (PubMed:20023638, PubMed:20622853). Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3 (PubMed:20023638). Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate (PubMed:20622853). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Nucleus.
| Keywords: | Anti-KDM7A, Anti-JHDM1D, Anti-Lysine-specific demethylase 7, Anti-Lysine-specific demethylase 7A, Anti-[histone H3]-dimethyl-L-lysine9 demethylase 7A, Anti-JmjC domain-containing histone demethylation protein 1D, KDM7 rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES19795 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | Synthesized peptide derived from human KDM7 AA range: 217-267 |
| Format: | Purified |
Database Information
| KEGG ID : | K11445 | Matching products |
| UniProt ID : | Q6ZMT4 | Matching products |
| Gene ID | GeneID 80853 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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