Anti-IRE1 alpha, Internal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64730.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its... more

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Product information "Anti-IRE1 alpha, Internal"

Protein function: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. [The UniProt Consortium]

Keywords:	Anti-IRE1a, Anti-hIRE1p, Anti-Ire1-alpha, EC=2.7.11.1, EC=3.1.26.-, Anti-Endoribonuclease, Anti-Inositol-requiring protein 1, Anti-Serine/threonine-protein kinase, Anti-Endoplasmic reticulum-to-nucleus signaling 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64730

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, canine, swine, bovine)
Immunogen:	C-PNAHGKIKAMISD
Format:	Ammonium Sulfate Precipitated