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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
I8443-18T.100 | 100 µg | - | - |
3 - 19 business days* |
978.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Interleukin 22 (IL-22), also called IL-10-related T cell-derived inducible factor or IL-TIF, is a... more
Product information "Anti-Interleukin 22 (IL-22, IL-10 Related T cell-derived Inducible Factor, IL-TIF)"
Interleukin 22 (IL-22), also called IL-10-related T cell-derived inducible factor or IL-TIF, is a secreted cytokine that contributes to the inflammatory response in vivo. IL-22 is expressed in T cells and mast cells in response to IL-9 or lipopolysaccharide. IL-22 monomers bind to a class II cytokine receptor that is a heterodimer of CRF2-9 (IL-22 Ra1) and CRF2-4 (IL-10 Rb). Human IL-22 is a 179aa protein with a 33aa signal peptide, three N-glycosylation sites and two intramolecular disulfide bonds, the mature protein shows 81% and 77% aa identity with mouse and rat IL-22, respectively. Applications: Suitable for use in ELISA and Neutralization. Other applications not tested. Recommended Dilution: Neutralization: Measured by its ability to neutralize IL-22induced IL-10 secretion in the COLO 205 human colorectal adenocarcinoma cell line. Nagalakshmi, M.L. et al. (2004) Intl. Immunopharmacol. 4:679. The Neutralization Dose (ND50) is typically 1-5ug/ml in the presence of 1ng/ml recombinant human IL-22. Optimal dilutions to be determined by the researcher. , Hybridoma: , Myeloma cells with B cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-IL22, Anti-ILTIF, Anti-IL-22, Anti-IL-TIF, Anti-Interleukin-22, Anti-Cytokine Zcyto18, Anti-IL-10-related T-cell-derived-inducible factor |
Supplier: | United States Biological |
Supplier-Nr: | I8443-18T |
Properties
Application: | ELISA, Neutr. |
Antibody Type: | Monoclonal |
Clone: | 11D67 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant human IL-22 (aa 34-179) expressed in E. coli (Accession #Q9GZX6) |
Format: | Affinity Purified |
Database Information
KEGG ID : | K05445 | Matching products |
UniProt ID : | Q9GZX6 | Matching products |
Gene ID | GeneID 50616 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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