Anti-human CD340, clone 24D2, iFluor(TM) 350

Anti-human CD340, clone 24D2, iFluor(TM) 350
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABD-13400010 100 tests -

3 - 8 business days*

911.00€
ABD-13400011 500 tests -

3 - 8 business days*

3,414.00€
 
iFluor 350 Protein function: Protein tyrosine kinase that is part of several cell surface... more
Product information "Anti-human CD340, clone 24D2, iFluor(TM) 350"
iFluor 350 Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. [The UniProt Consortium], iFluor(TM) 350 Anti-human CD340 Antibody *24D2*
Keywords: Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene c-ErbB-2, Anti-Metastatic lymph node gene 19 protein, Anti-Receptor tyrosine-protein kinase erbB-2, iFluor(TM) 350 Anti-human CD340 A
Supplier: AAT Bioquest
Supplier-Nr: 1340001

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: 24D2
Conjugate: iFluor 350
Host: Mouse
Species reactivity: human
Format: Affinity Purified

Handling & Safety

Storage: +4°C (protect from light)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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