494 products were found matching "K05083"!

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Anti-ErbB2
Anti-ErbB2

Item number: A300-621A-T

ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain...
Keywords: Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: WB, IP, IHC
Host: Rabbit
Species reactivity: human
164.00€ *
Review
Anti-ErbB2
Anti-ErbB2

Item number: A300-622A-T

ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain...
Keywords: Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: WB, IP, IHC
Host: Rabbit
Species reactivity: human
164.00€ *
Review
Anti-ErbB2
Anti-ErbB2

Item number: A300-623A-T

ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain...
Keywords: Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: WB, IP, IHC
Host: Rabbit
Species reactivity: human
164.00€ *
Review
Anti-HER2 / ErbB2 / C-terminal region
Anti-HER2 / ErbB2 / C-terminal region

Item number: NSJ-F54939-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, althought neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin....
Keywords: Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: IHC (paraffin), WB
Host: Rabbit
Species reactivity: human
From 326.00€ *
Review
Anti-HER2 / ErbB2
Anti-HER2 / ErbB2

Item number: NSJ-RQ7075

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene. And it is also frequently called HER2 (from human...
Keywords: Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: WB, IHC (paraffin), Direct ELISA
Host: Rabbit
Species reactivity: human, mouse
755.00€ *
Review
Anti-HER2 / ErbB2
Anti-HER2 / ErbB2

Item number: NSJ-RQ7168

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene. And it is also frequently called HER2 (from human...
Keywords: Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: WB, IHC (paraffin), FC, Direct ELISA
Host: Rabbit
Species reactivity: human
755.00€ *
Review
Anti-HER-2 (Trastuzumab Biosimilar In Vivo Antibody)
Anti-HER-2 (Trastuzumab Biosimilar In Vivo Antibody)

Item number: G-IVMB0215.1

Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with...
Keywords: Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: CyTOF ELISA, FC, IHC
Host: Human
Species reactivity: human
From 266.00€ *
Review
Anti-HER-2 (Trastuzumab Biosimilar In Vivo Antibody (Fc Reduced))
Anti-HER-2 (Trastuzumab Biosimilar In Vivo Antibody (Fc...

Item number: G-IVMB0216.500

Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with...
Keywords: Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene...
Application: CyTOF, ELISA, FC, IHC
Host: Human
Species reactivity: human
620.00€ *
Review
Lapatinib
Lapatinib

Item number: Cay11493-5

Lapatinib is a dual inhibitor of the EGF receptor (EGFR) and ErbB2 (IC50s = 19 and 3 nM, respectively). It inhibits the growth of EGFR-overexpressing A431 skin cancer and ErbB2-overexpressing SK-BR-3 breast cancer cells (IC50s = 0.14 and 0.124 µM, respectively). Lapatinib also inhibits the growth of ErbB2-amplified...
Keywords: GSK 572016, GW 572016,...
Application: EGFR / HER2 inhibitor
CAS 231277-92-2
MW: 581.1 D
From 77.00€ *
Review
Afatinib
Afatinib

Item number: Cay11492-5

Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
Keywords: BIBW 2992,...
Application: EGFR / HER2 kinase inhibitor
CAS 850140-72-6
MW: 485.9 D
From 35.00€ *
Review
Afatinib
Afatinib

Item number: LKT-A2077.5

Afatanib is an anticancer chemotherapeutic compound that has been approved to treat advanced lung cancers such as non-small cell lung cancer (NSCLC) and is in clinical trials as a potential treatment for other advanced solid tumors such as breast cancer and colorectal cancer. Afatanib exerts its anticancer activity...
Keywords: BIBW 2992
Application: EGFR / ErbB2 inhibitor
MW: 485.94 D
From 167.00€ *
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AG-879
AG-879

Item number: Cay10793-5

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors. AG-879 is a tyrphostin compound that inhibits nerve growth factor...
Keywords: Tyrphostin AG-879, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2E-propenethioamide
Application: Tyrosine kinase inhibitor
CAS 148741-30-4
MW: 316.5 D
From 86.00€ *
Review
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