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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-AB-F1175E.200 | 200 tests | - |
7 - 16 business days* |
386.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD... more
Product information "Anti-Human CD273/PD-L2, APC conjugated, clone 24F.10C12"
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. Protein function: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [The UniProt Consortium]
Keywords: | Anti-B7DC, Anti-PD-L2, Anti-CD273, Anti-B7-DC, Anti-PDCD1LG2, Anti-PD-1 ligand 2, Anti-PDCD1 ligand 2, Anti-Butyrophilin B7-DC, Anti-Programmed death ligand 2, Anti-Programmed cell death 1 ligand 2, APC Anti-Human CD273/PD-L2 Antibody[24F.10C12] |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-F1175E |
Properties
Application: | FC, FC (membrane) |
Antibody Type: | Monoclonal |
Clone: | 24F.10C12 |
Conjugate: | APC |
Host: | Mouse |
Species reactivity: | human |
Database Information
KEGG ID : | K06708 | Matching products |
UniProt ID : | Q9BQ51 | Matching products |
Gene ID | GeneID 80380 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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