70 products were found matching "Q9BQ51"!

Protein function: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [The UniProt Consortium]

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDCD1LG2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDCD1LG2....

CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed...

CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed...

The recombinant expression vectors are designed to express human engineered T cell receptor (TCR) activator and human PD-L2 (GenBank Accession #NM_025239) in mammalian cells. The transfected cells can be used in conjunction with PD-1/NFAT Reporter/Jurkat T cells (BPS #60535) to study the interactions of PD-1 with...

Human secreted Programmed Death Ligand 2 (PDL2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, expressed in a HEK293 cell expression system. MW = 49. Protein function: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG...

Human secreted Programmed Death Ligand 2 (PDL2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, with C-terminal Avi-tag, expressed in a HEK293 cell expression system. MW = 51. Protein function: Involved in the costimulatory signal, essential for T- cell...

Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand attenuates immune responses and is exploited by both tumors and viruses. The PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. This kit comes in a convenient 96-well...

Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand attenuates immune responses and is exploited by both tumors and viruses. The PD-L2 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. This kit comes in a convenient 96-well format, with...

The PD-1:PD-L2 TR-FRET Assay Kit is designed to measure the inhibition of PD-1 binding to PD-L2 in a homogeneous 384 reaction format. Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand attenuates immune responses and is exploited by both tumors and viruses. This FRET-based assay requires no...

The PD-1:PD-L2 Homogeneous Assay Kit is designed to measure the inhibition of PD-1 binding to PD-L2. With this kit, only three simple steps on a microtiter plate are required. First, a sample containing PD-1 and an inhibitor of choice is incubated with the biotinylated PD-L2 for 60 minutes. Next, acceptor beads are...

The PD-1/PD-L2 Inhibitor Screening Cell-Based Assay is a bioluminescent cell-based assay that can be used to screen and profile inhibitors of the PD-1:PD-L2 interaction. The assay consists of two main components: * Growth-Arrested PD-1 Effector cells (PD-1/NFAT reporter-Jurkat cells): Reporter Jurkat T cells...