Anti-Human CD11a (Clone: DF1524)

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ABE-10-4145-100	100 µg		-		3 - 11 business days*		15 %	205.00€ 174.25€

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Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.... more

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Product information "Anti-Human CD11a (Clone: DF1524)"

Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R (PubMed:11812992, PubMed:15528364). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis. Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). [The UniProt Consortium]

Keywords:	Anti-ITGAL, Anti-CD11a, Anti-CD11A, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A, Anti-Leukocyte adhesion glycoprotein LFA-1 alpha chain, Anti-Leukocyte function-associated molecule 1 alpha chain, Monoclonal Antibody to Human
Supplier:	Abeomics
Supplier-Nr:	10-4145

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	DF1524
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	full length Recombinant protein of human CD11a was used as immunogen for this antibody.
Format:	Purified