434 products were found matching "K05718"!
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BIRT 377
Item number: Cay43171-10
BIRT 377 is a negative allosteric modulator (NAM) of lymphocyte function-associated antigen-1 (LFA-1). It binds to LFA-1 at a site distal to residues involved in intercellular adhesion molecule interactions and induces a conformational change to its inactive state. BIRT 377 selectively inhibits the interaction of...
| Keywords: | (5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione |
| Application: | Negative allosteric lymphocyte function-associated antigen-1 (LFA-1) modulator |
| CAS | 213211-10-0 |
| MW: | 442.13 D |
From 231.00€
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Anti-CD11a (bovine), clone HUH73A
Item number: WS0586B-100
The monoclonal antibody was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.
| Keywords: | Anti-CD11a, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A, Anti-Leukocyte... |
| Application: | FC, IHC, Cell Function |
| Host: | Mouse |
| Species reactivity: | bison, bovine, caprine, dog, human, ovine |
343.00€
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Anti-LFA-1
Item number: NSJ-R36394-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Lymphocyte function-associated antigen 1, CD11A, integrin alpha L (ITGAL) Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety...
| Keywords: | Anti-CD11A, Anti-ITGAL, Anti-CD11a, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | WB, IHC, ELISA (peptide) |
| Host: | Goat |
| Species reactivity: | human |
836.00€
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Lifitegrast
Item number: Cay22588-10
Lifitegrast is an inhibitor of the protein-protein interaction between lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1). It binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits the...
| Keywords: | SAR 1118,... |
| Application: | CD11A blocker |
| CAS | 1025967-78-5 |
| MW: | 615.5 D |
From 49.00€
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Anti-CD11a / LFA-1
Item number: NSJ-R32698
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CD11a, also known as ITGAL or LFA-1, is a human gene which functions in the immune system. It is mapped to 16p11.2. CD11a is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. CD11a encodes the integrin alpha L...
| Keywords: | Anti-ITGAL, Anti-CD11a, Anti-CD11A, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | WB, FC, ICC |
| Host: | Rabbit |
| Species reactivity: | human |
790.00€
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Anti-CD11a / LFA-1 alpha, clone I21/7
Item number: ARG20829.100
| Keywords: | Anti-Integrin alpha-L |
| Application: | FC, IHC (frozen), ICC, IF, IP, BL |
| Host: | Rat |
| Species reactivity: | mouse |
586.00€
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Anti-CD11a / LFA-1 alpha (FITC), clone I21/7
Item number: ARG20830.100
| Keywords: | Anti-Integrin alpha-L |
| Application: | FC, IHC (frozen), ICC, IF, BL |
| Host: | Rat |
| Species reactivity: | mouse |
625.00€
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Anti-CD11a / LFA-1 alpha (PE-Cy7), clone I21/7
Item number: ARG20834.50
| Keywords: | Anti-Integrin alpha-L |
| Application: | FC, IHC (frozen), ICC, IF, BL |
| Host: | Rat |
| Species reactivity: | mouse |
518.00€
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Anti-CD11a / LFA-1 alpha (Biotin), clone 38
Item number: ARG21252.50
Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
| Keywords: | Anti-CD11a, Anti-CD11A, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | FC, IHC (frozen), FA (blocking), ELISA |
| Host: | Mouse |
| Species reactivity: | human |
427.00€
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Anti-CD11a / LFA-1 alpha (PE), clone 38
Item number: ARG21253.50
Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
| Keywords: | Anti-CD11a, Anti-CD11A, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | FC, IHC (frozen), FA (blocking), ELISA |
| Host: | Mouse |
| Species reactivity: | human |
493.00€
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Anti-CD11a, clone MEM-25 (APC)
Item number: ARG53758.100
Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
| Keywords: | Anti-ITGAL, Anti-CD11A, Anti-CD11a, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | FC, IP, FA |
| Host: | Mouse |
| Species reactivity: | human |
734.00€
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Anti-CD11a, clone MEM-25 (PE)
Item number: ARG53759.100
Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
| Keywords: | Anti-ITGAL, Anti-CD11A, Anti-CD11a, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | FC |
| Host: | Mouse |
| Species reactivity: | human |
734.00€
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