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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2511.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2511.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
mitogen-activated protein kinase kinase kinase kinase 4(MAP4K4) Homo sapiens The protein encoded... more
Product information "Anti-HGK"
mitogen-activated protein kinase kinase kinase kinase 4(MAP4K4) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], Protein function: Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr- 322. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Cytoplasm .
Keywords: | Anti-HGK, Anti-MAP4K4, Anti-MEKKK 4, EC=2.7.11.1, Anti-MEK kinase kinase 4, Anti-Nck-interacting kinase, Anti-HPK/GCK-like kinase HGK, Anti-MAPK/ERK kinase kinase kinase 4, Anti-Mitogen-activated protein kinase kinase kinase kinase 4, HGK rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2511 |
Properties
Application: | WB, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | The antiserum was produced against synthesized peptide derived from human MEKKK 4. AA range:406-455 |
MW: | 142 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K04407 | Matching products |
UniProt ID : | O95819 | Matching products |
Gene ID | GeneID 9448 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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