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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded... more
Product information "Anti-HEXA"
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Protein function: Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. [The UniProt Consortium]
Keywords: | Anti-HEXA, EC=3.2.1.52, Anti-Hexosaminidase subunit A, Anti-Beta-hexosaminidase subunit alpha, Anti-Beta-N-acetylhexosaminidase subunit alpha, Anti-N-acetyl-beta-glucosaminidase subunit alpha, HEXA Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-64175 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human HEXA |
Database Information
KEGG ID : | K12373 | Matching products |
UniProt ID : | P06865 | Matching products |
Gene ID | GeneID 3073 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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