85 products were found matching "K12373"!

Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Gangliosides isolated from apoptogenic glioblastoma multiforme (GBM) cells are enriched in ganglioside GM2 compared with nonapoptogenic GBM cells, and ganglioside GM2 induces activated T cell death when used at a...

4-Nitrophenyl-N-acetyl-beta-D-glucosaminide is a chromogenic substrate for N-acetyl-beta-glucosaminidase. Hydrolysis of 4-nitrophenyl-N-acetyl-beta-D-glucosaminide by N-acetyl-beta-glucosaminidase releases 4-nitrophenol, which can be quantified by colorimetric detection at 405 nm as a measure of...

4-Methylumbelliferyl-2-acetamido-2-deoxy-beta-D-glucopyranoside is a fluorogenic substrate for beta-hexosaminidases. Upon enzymatic cleavage by beta-hexosaminidases, 4-methylumbelliferone (4-?U) is released and its fluorescence can be used to quantify beta-hexosaminidase activity. 4-MU fluorescence is pH-dependent...

Protein function: Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. [The UniProt Consortium]

Human hexosaminidase A (alpha polypeptide), also known as HEXA, (GenBank Accession No. NM_000520), full length (amino acids 1-529(end)) with C-terminal FLAG-His-tags, MW = 62.5 kDa, expressed in a baculovirus infected Sf9 cell expression system

0.5mg/ml if reconstituted with 0.2ml sterile DI water. HEXA (Hexosaminidase A) is an enzyme that in humans is encoded by the HEXA gene. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines The HEXA gene...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Hexosaminidase A (alpha polypeptide) is an enzyme that in humans is encoded by the HEXA gene. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Hexosaminidase beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of...

Protein function: Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. [The UniProt Consortium]

0.5mg/ml if reconstituted with 0.2ml sterile DI water. HEXA, hexosaminidase A (alpha polypeptide), is an enzyme that in humans is encoded by the HEXA gene. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl...

Protein function: Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides (PubMed:11707436, PubMed:9694901, PubMed:8672428, PubMed:8123671). The...