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Discount Promotion
Promotion:
Get 15% Discount on Antibodies and Biosimilars by Abeomics!
*1
*1 Offer expires 30/06/2024
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ABE-11-8085-100 | 100 µg | - |
3 - 11 business days* |
15 %
|
387.00€
328.95€ |
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
GAB1 (GRB2-associated-binding protein 1) belongs to the scaffolding adaptor protein family. GAB1... more
Product information "Anti-Grb2-associated binder 1"
GAB1 (GRB2-associated-binding protein 1) belongs to the scaffolding adaptor protein family. GAB1 has an N-terminal pleckstrin homology domain, as well as multiple tyrosine-based motifs and proline-rich sequences, which are potential binding sites for various Src homology 2 (SH2) domains and Src homology 3 domains, respectively. It is required for fibroblast cell survival and maintaining cardiac function. It is expressed in myocardial tissue in acyanotic and cyanotic children with congenital heart defects (26090437). GAB1 is an important docking protein responsible for intracellular signaling assembly and transduction. It is involved in proliferation and apoptosis in human chondrosarcoma (CS). It plays a role in FGFR1 signaling and involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Protein function: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway (PubMed:29408807). [The UniProt Consortium]
Keywords: | Anti-GAB1, Anti-GRB2-associated binder 1, Anti-GRB2-associated-binding protein 1, Anti-Growth factor receptor bound protein 2-associated protein 1, Polyclonal Antibody to Grb2-associated binder 1 |
Supplier: | Abeomics |
Supplier-Nr: | 11-8085 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A partial length recombinant Grb2-associated binder 1 protein (amino acids 110-320) was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K09593 | Matching products |
UniProt ID : | Q13480 | Matching products |
Gene ID | GeneID 2549 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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