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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-PACO26937.50 | 50 µg | - |
9 - 20 business days* |
363.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Gdf5 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Mouse and for... more
Product information "Anti-Gdf5"
Gdf5 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Mouse and for use in ELISA, IHC applications. Gdf5 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG. Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (PubMed:24076600). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [The UniProt Consortium]
| Keywords: | Anti-Gdf5, Anti-Bmp14, Anti-GDF-5, Anti-BMP-14, Anti-Bone morphogenetic protein 14, Anti-Growth/differentiation factor 5 |
| Supplier: | Assay Genie |
| Supplier-Nr: | PACO26937 |
Properties
| Application: | ELISA, IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | mouse |
| Immunogen: | Recombinant Mouse Growth/differentiation factor 5 protein (376-495AA) |
Database Information
| KEGG ID : | K04664 | Matching products |
| UniProt ID : | P43027 | Matching products |
| Gene ID | GeneID 14563 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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