Anti-GABRB2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA067632.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA067632.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Ligand-gated chloride channel which is a component of the heteropentameric... more

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Product information "Anti-GABRB2"

Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:8264558, PubMed:19763268, PubMed:27789573, PubMed:29950725). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750). Functions also as histamine receptor and mediates cellular responses to histamine. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-GABRB2, Anti-GABA(A) receptor subunit beta-2, Anti-Gamma-aminobutyric acid receptor subunit beta-2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA067632

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: STLEIKNEMA TSEAVMGLGD PRSTMLAYDA SSIQYRKAGL PRHSFGRNAL ERHVAQKKSR (ATA-APrEST88690)