99 products were found matching "K05181"!

An analytical reference standard categorized as a barbiturate, has anesthetic and anti-convulsant effects in rats, regulated as a Schedule III compound in the United States, intended for research and forensic applications. SMILES: O=C1C(CC)(C(C)CCC)C(NC(N1)=S)=O. InChi Code:...

Milbemectin is a mixture of milbemycin A3 (30%, Cay-18360) and milbemycin A4 (70%, Cay-17155) that has acaricidal and nematocidal activity against adult spider mites, spider mite eggs, and C. elegans with IC50 values of 5.3, 41.1, and 9.5 µg/ml, respectively. It acts as an allosteric agonist of the Drosophila RDL...

Picrotoxin is a natural plant-derived poison that acts as a selective GABAA receptor antagonist. It is functional in vivo and is used to study the role of GABAA receptors in the central nervous system as well in the periphery. Picrotoxin induces seizures in adult and immature animals and is used to study...

Anti-GABA(A) Receptor beta 3 pS408/pS409 Antibody is directed against rat GABA(A) Receptor beta 3. The antibody was affinity purified from monospecific antiserum by immunoaffintiy purification. Immunolabeling of the GABAA band is completely blocked by the phospho-peptide used as antigen but not by the corresponding...

(+)-Kavain is a kavalactone and the major constituent of the pepper plant kava (P. methysticum) and has diverse biological activities. It is a positive allosteric modulator of alpha4beta2delta subunit-containing GABAA receptors with EC50 values of 25 and 59 µM in the presence and absence of 300 µM (+)-kavain,...

Bretazenil is a positive allosteric modulator of GABAA receptors with anticonvulsant and anxiolytic activity. It potentiates GABA-gated chloride currents in rat cortical neurons and in HEK293 cells expressing alpha1beta1gamma2 subunit-containing GABAA receptors (EC50s = 60 and 10 nM, respectively). Bretazenil...

Protein function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital, these are bound...

Anti-GABA-A receptor alpha 1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with GABA-A receptor alpha 1 from mouse, human, and rat based on 100% homology with the immunizing sequence. No cross-reactivity against GABA-A-R-Beta 2 or -Beta3. Cross-reactivity...

Anti-GABA-A receptor Beta3 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with GABA-A receptor Beta3 from human, mouse, and rat based on 100% homology with the immunizing sequence. No cross-reactivity against GABA-A-R-Beta 2 or -Beta1. Cross-reactivity with...

Anti-GABA(A) Receptor beta 3 Antibody is directed against rat GABA(A) Receptor beta 3. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse. Cross reactivity with GABA(A) Receptor beta 3...

Anti-GABA(A) Receptor beta 1 Antibody is directed against rat GABA(A) Receptor beta 1. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: bovine chicken, canine, human, mouse non-human...

Anti-GABA(A) Receptor beta 2 Antibody is directed against rat GABA(A) Receptor beta 2. The antibody wasaffinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: canine,human, mouse and non-human primates. Protein...