Anti-FBP17

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-791A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A302-791A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: May act as a link between RND2 signaling and regulation of the actin... more

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Product information "Anti-FBP17"

Protein function: May act as a link between RND2 signaling and regulation of the actin cytoskeleton. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL. [The UniProt Consortium]

Keywords:	Anti-FBP17, Anti-FNBP1, Anti-hFBP17, Anti-Formin-binding protein 1, Anti-Formin-binding protein 17
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-791A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-791A-T maps to a region between residue 567 and 617 of human Formin-Binding Protein 17 using the numbering given in entry NP_055848.1 (GeneID 23048).
Format:	Antigen Affinity Purified