Anti-FBP17 / FNBP1, Internal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG63662.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: May act as a link between RND2 signaling and regulation of the actin... more

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Product information "Anti-FBP17 / FNBP1, Internal"

Protein function: May act as a link between RND2 signaling and regulation of the actin cytoskeleton. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL. [The UniProt Consortium]

Keywords:	Anti-FNBP1, Anti-FBP17, Anti-hFBP17, Anti-Formin-binding protein 1, Anti-Formin-binding protein 17
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG63662

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, canine, swine, bovine)
Immunogen:	KQLESSKRRFERDC
Format:	Ammonium Sulfate Precipitated