Anti-Dysbindin1

Anti-Dysbindin1
Promotion:

Bethyl is giving away a free permanent marker for every Bethyl purchase until supplies last!

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-360A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: Component of the BLOC-1 complex, a complex that is required for normal... more
Product information "Anti-Dysbindin1"
Protein function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway. [The UniProt Consortium]
Keywords: Anti-My031, Anti-DTNBP1, Anti-BLOC1S8, Anti-Dysbindin, Anti-Dysbindin-1, Anti-HPS7 protein, Anti-BLOC-1 subunit 8, Anti-Dystrobrevin-binding protein 1, Anti-Hermansky-Pudlak syndrome 7 protein
Supplier: Bethyl Laboratories
Supplier-Nr: A303-360A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide. The epitope recognized by A303-360A maps to a region between residue 301 and 351 of human Dystrobrevin Binding Protein 1 using the numbering given in entry NP_115498.2 (GeneID 84062).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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