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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A303-359A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A303-359A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
Protein function: Component of the BLOC-1 complex, a complex that is required for normal... more
Product information "Anti-Dysbindin1"
Protein function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway. [The UniProt Consortium]
Keywords: | Anti-My031, Anti-DTNBP1, Anti-BLOC1S8, Anti-Dysbindin, Anti-Dysbindin-1, Anti-HPS7 protein, Anti-BLOC-1 subunit 8, Anti-Dystrobrevin-binding protein 1, Anti-Hermansky-Pudlak syndrome 7 protein |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A303-359A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: orangutan, rhesus monkey, gorilla, crab-eating macaque, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A303-359A-T maps to a region between residue 251 and 301 of human Dystrobrevin Binding Protein 1 using the numbering given in entry NP_115498.2 (GeneID 84062). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K20189 | Matching products |
UniProt ID : | Q96EV8 | Matching products |
Gene ID | GeneID 84062 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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