Anti-DACH1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-555A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A303-555A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Transcription factor that is involved in regulation of organogenesis. Seems to... more

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Product information "Anti-DACH1"

Protein function: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin- dependent kinase inhibitors, including the p27Kip1 promoter. Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain. [The UniProt Consortium]

Keywords:	Anti-DACH, Anti-DACH1, Anti-Dach1, Anti-Dachshund homolog 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-555A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide. The epitope recognized by A303-555A-T maps to a region between residue 720 and 740 of human Dachshund Homolog 1 using the numbering given in entry CAH73005.1 (GeneID 1602).
Format:	Antigen Affinity Purified